Journal of the National Cancer Institute
Promising biomarker and candidate tumor suppressor gene identified for colorectal cancer
Published in Gastroenterology Week, June 29th, 2009
In the study, Manon van Engeland, Ph.D., of the Department of Pathology at Maastricht University Medical Center in the Netherlands, and colleagues examined N-Myc downstream-regulated gene 4 (NDRG4) as a novel tumor suppressor and biomarker.
The researchers analyzed NDRG4 promoter methylation and expression in human colorectal cancer cell lines, noncancerous colon mucosa, and colorectal cancer tissue....
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