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BioMed Central

Gene map aims to combat blood flukes

Published in Gastroenterology Week, July 13th, 2009

The first microsatellite-based genetic linkage map has been published for Schistosoma mansoni, a blood fluke that is known to infect over 90 million people in Africa, the Middle East and the New World. Researchers writing in BioMed Central's open access journal Genome Biology hope the map will stimulate research and open doors to new advances in combating this neglected human pathogen.

S. mansoni, a blood fluke, is one of the major causes of schistosomiasis, a chronic disease, with varying symptoms depending on the organs affected. Individuals with intestinal infections develop an apparent 'potbelly'. Acute, hepatic and intestinal schistosomiasis are all commonly seen....

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