Gastroenterology Week
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Ulcerative Colitis
Study results from Jikei University, Medical Department update understanding of ulcerative colitis
July 13th, 2009
According to recent research from Kashiwa, Japan, "Interleukin 2 (IL-2)- and IL-10-knockout mice develop spontaneous colitis under conventional but not germ-free conditions, suggesting that commensal bacteria play an important role in the pathogenesis of colitis. However, interactions between commensal bacteria and colonic epithelial cells have not been fully investigated." "We therefore assessed the ability of various commensal bacteria and probiotics to adhere to and invade colonic epithelial cells. Effects of the bacteria on production of proinflammatory cytokines were also measured. Commensal bacteria, including mucosal organisms isolated from ulcerative colitis...
Source: Gastroenterology Week (2009-07-13)
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