DNA Research
Research reports from Gifu University provide new insights into DNA research
Published in Gastroenterology Week, July 13th, 2009
Data detailed in 'Global DNA hypomethylation suppresses squamous carcinogenesis in the tongue and esophagus' have been presented. According to a study from Gifu, Japan, "Genome-wide DNA hypomethylation and concomitant site-specific gene hypermethylation are among the most common molecular alterations in human neoplasia. Previous studies revealed that genetic reduction of the DNA methylation level results in opposing effects on tumor development, depending on the tumor cell type and on the different stages of the tumorigenesis."
"For instance, reduced levels of DNA methylation in mice strongly inhibited tumor development of the intestine, whereas they induced thymic...
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