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Protein Deficiency

Research conducted at University of Michigan, Medical Department has updated our knowledge about protein deficiency

Published in Gastroenterology Week, October 12th, 2009

"Dietary protein deficiency results in diminished capacity of the pancreas to secrete enzymes needed for macronutrient digestion. Previous work has suggested that modulation of the mammalian target of rapamycin (mTOR) pathway by the hormone cholecystokinin (CCK) plays an important role in normal digestive enzyme synthesis after feeding," scientists writing in the journal Gastroenterology report.

"The purpose of this Study was to elucidate the role of mTOR in protein deficiency-induced pancreatic dysfunction. Wild-type and CCK-null mice were fed protein-deficient chow for 4 days and then allowed to recover on control chow in the presence or absence of the mTOR...

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