Mass Spectrometry

New mass spectrometry study findings recently were published by A. Tarantini and co-researchers

Published in Gastroenterology Week, February 1st, 2010

"Polycyclic aromatic hydrocarbons (PAH) produced upon incomplete combustion of organic matter are suspected to be carcinogenic to humans. In the present work, we especially studied the genotoxicity of benzo[a]pyrene (B[a]P), pure or in mixtures, with emphasis placed on the contribution of oxidative stress and alkylation," scientists in Grenoble, France report.

"A comparison was made between the extent of DNA strand breaks as determined by the Comet assay and the number of DNA adducts to the diol epoxide metabolite of B[a]P measured by HPLC-mass spectrometry. HepG2 cultured human hepatocytes were treated with either pure B[a]P or particulate matter extracted from air...

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Source: Gastroenterology Week (2010-02-01)

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