Adenoma

Researchers at Federal University publish new data on adenoma

Published in Gastroenterology Week, February 8th, 2010

According to a study from Vicosa, Brazil, "We determined the effect of fish oil (FO) ingestion on colonic carcinogenesis in rats. Male Wistar rats received 4 subcutaneous injections (40 mg/kg body weight each) of 1,2-dimethylhydrazine (DMH) at 3-day intervals and were fed a diet containing 18% by weight FO (N = 10) or soybean oil (SO, N = 10) for 36 weeks."

"At sacrifice, the colon was removed, aberrant crypt foci were counted and the fatty acid profile was determined. Intestinal tumors were removed and classified as adenoma or carcinoma. Liver and feces were collected and analyzed for fatty acid profile. FO reduced the mean (+/- SEM) number of aberrant crypt foci...

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Source: Gastroenterology Week (2010-02-08)

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