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Pancreatic Cancer

Studies from E.A. Tevelde et al add new findings in the area of pancreatic cancer

Published in Gastroenterology Week, February 22nd, 2010

According to recent research published in the journal Ejso, "Despite surgical resection, pancreatic cancer carries a poor prognosis. In search for new molecular therapeutic targets, we investigated the expression of the HER-family and gene amplification of HER-2 in pancreatic adenocarcinomas of different stages."

"Tissue of 45 resected patients was analyzed for all HER-family 1-4 expression by immunohistochemistry and HER-2 gene amplification was assessed by multiplex ligation-dependent probe amplification and chromogenic in situ hybridization. The type of surgery, location, stage and grade of the tumor, as well as involvement of the resection margins were...

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