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Bioorganic and Medicinal Chemistry

Investigators at University Hospital, Faculty of Pharmaceutical Sciences release new data on bioorganic and medicinal chemistry

Published in Gastroenterology Week, August 16th, 2010

Investigators publish new data in the report 'Development and evaluation of a 68Ga labeled pamoic acid derivative for in vivo visualization of necrosis using positron emission tomography.' According to recent research published in the journal Bioorganic & Medicinal Chemistry, "In this study, we labeled N,N'-bis(diethylenetriamine pentaacetic acid)-pamoic acid bis-hydrazide (bis-DTPA-PA) with the generator produced PET radionuclide gallium-68 and evaluated 68Ga-bis-DTPA-PA as a potential tracer for in vivo visualization of necrosis by positron emission tomography (PET). Radiolabeling was achieved with a decay-corrected radiochemical yield of 63%."

"Biodistribution...

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