Crohn's Disease

Findings from K. Mitsuyama and Co-Researchers Advance Knowledge in Crohn's Disease

Published in Gastroenterology Week, October 10th, 2011

2011 OCT 10 -- According to the authors of a study from Ibaraki, Japan, "Phage display technology has been utilized to select target molecules against circulating antibodies. The aims of this study were to isolate a peptide that binds with serum from Crohn's disease (CD) patients and to examine its diagnostic and pathogenic significance."

"A phage display library was constructed using cDNA from Caco-2 cells. Affinity selection using this cDNA library and serum samples from patients with CD was then performed. Phage clones that specifically reacted with the CD sera were then selected using a phage enzyme-linked immunosorbent assay (ELISA). After the DNA...

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Source: Gastroenterology Week (2011-10-10)

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