Autoimmune Pancreatitis

Data on Autoimmune Pancreatitis Detailed by T. Kusuda and Co-Authors

Published in Gastroenterology Week, October 17th, 2011

2011 OCT 17 -- "Immunoglobulin G4 (IgG4)-related autoimmune pancreatitis (AIP) is a new clinical entity of pancreatic disorder. There are immunologic and histological abnormalities, including increased serum IgG4 levels and the infiltration of IgG4-positive plasmacytes," researchers in Osaka, Japan report.

"However, the role of IgG4 is unclear. Recently, regulatory T cells (Tregs) were reported to contribute to the development of various autoimmune diseases as well as in B-cell shifting to IgG4-producing plasmacytes. We studied Tregs in the pancreas and peripheral blood. We recruited 44 patients with IgG4-related AIP. For comparison, we recruited 37...

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Source: Gastroenterology Week (2011-10-17)

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