Chronic Pain

Study Results from Fu Jen Catholic University Provide New Insights into Chronic Pain

Published in Gastroenterology Week, February 6th, 2012

2012 FEB 6 -- "The chronic, persistent pain associated with chronic pancreatitis (CP) has many characteristics of neuropathic pain, initiated and maintained by the activation of spinal microglia. We investigated whether activated microglia in the thoracic spinal cord contribute to chronic pain in a rat model of CP," researchers in Taipei, Taiwan report.

"CP was induced in Sprague-Dawley rats by an intraductal injection of 2% trinitrobenzene sulfonic acid. Hyperalgesia was assessed by the measurement of mechanical sensitivity of the abdomen and nocifensive behavior to electrical stimulation of the pancreas. Three weeks after induction of CP, spinal samples...

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Source: Gastroenterology Week (2012-02-06)

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