Epithelial Cells
Studies from Brown University Describe New Findings in Epithelial Cells
Published in Gastroenterology Week, February 6th, 2012
2012 FEB 6 -- New investigation results, "ATP: a mediator for HCl-induced TRPV1 activation in esophageal mucosa," are detailed in a study published in American Journal of Physiology Gastrointestinal and Liver Physiology. "In esophageal mucosa, HCl causes TRPV1-mediated release of calcitonin gene-related peptide (CGRP) and substance P (SP) from submucosal neurons and of platelet-activating factor (PAF) from epithelial cells. CGRP and SP release was unaffected by PAF antagonists but reduced by the purinergic antagonist suramin," scientists writing in the American Journal of Physiology Gastrointestinal and Liver Physiology report.
"ATP caused...
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