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Cirrhosis

University of California Details Research in Cirrhosis

Published in Gastroenterology Week, February 6th, 2012

2012 FEB 6 -- A report, "Primary biliary cirrhosis and autoimmune hepatitis: apotopes and epitopes," is newly published data in Journal of Gastroenterology. "Autoimmune liver diseases (ALDs) represent a wide spectrum of chronic inflammatory diseases that are characterized by an immune-mediated attack against either hepatocytes (in the case of autoimmune hepatitis types 1 and 2, AIH-1, 2) or cholangiocytes (in primary biliary cirrhosis, PBC). PBC is considered a model autoimmune disease due to the homogeneity of patients, the high specificity of antimitochondrial antibodies (AMAs), and the specificity of biliary epithelial cell (BEC) destruction," researchers in Davis,...

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