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Cancer/Gene Therapy

Retroviral Vector Effective Against Brain Tumors

Published in Gene Therapy Weekly, February 13th, 1995

At the 17th Annual Bristol-Myers Squibb Cancer Research Symposium, R. Michael Blaese of the U.S. National Cancer Institute shared the results of experimental therapies involving the introduction of genes that alter the sensitivity of tumors to various drugs.

The technique represents an indirect gene therapy approach to cancer that Blaese says has already met with some success.

Blaese described suicide genes to those in attendance at the symposium, which was sponsored by the University of California, Los Angeles (UCLA), Extension and the Jonsson Comprehensive Cancer Center at UCLA. These genes encode for relatively benign gene products that activate...

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