Published in Gene Therapy Weekly, February 13th, 1995
Retroviral vectors offer a reliable alternative to transfection and electroporation as a means to introduce foreign genes into cells in vitro and have shown promise for the application of gene therapy in vivo. Normally, retroviral vectors infect a packaging cell line, which then infects the target cells, and cannot reproduce. In some instances, however, progeny of the retroviral vectors may be...
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