Conference Coverage

Scientists Create Vaccine That Self-Destructs on Cue

Published in Gene Therapy Weekly, February 13th, 1995

Scientists searching for a safe HIV vaccine said they have created one with a built-in time bomb - a gene that will cleanse it from the body on cue.

Researchers believe the most effective HIV vaccine is likely to be a live virus, which will prime the body to mount a spirited reaction to HIV. Many, though, worry about giving healthy people even a weakened form of HIV, since it might cause cancer, immune suppression or even AIDS.

So now a team from the U.S. National Institute of Allergy and Infectious Diseases has come up with a novel strategy: a live but weakened HIV virus that can be killed off once it does its job.

A team...

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Source: Gene Therapy Weekly (1995-02-13)

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