Glanzmann's Thrombasthenia

Gene Mutation Associated with Bleeding Disorder

Published in Gene Therapy Weekly, February 20th, 1995

Researchers reported on type I Glanzmann's thrombasthenia in an Iranian-Jewish family that is associated with deletion-insertion and alternative splicing in the glycoprotein IIb gene.

Glanzmann's thrombasthenia is a bleeding disorder which is characterized by a decrease or an absence of the functional platelet membrane glycoprotein (GP) complex, GPIIb/IIIa ((alpha)_IIb (beta)₃ ).

Hava Peretz, Chaim Sheba Medical Center, Tel-Hashomer, Israel, and colleagues described the new deletion-insertion mutation in the GPIIb gene responsible for causing type I Glanzmann's thrombasthenia in two siblings of a blood-related Iranian-Jewish...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of Gene Therapy Weekly

Source: Gene Therapy Weekly (1995-02-20)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry