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Cancer/Gene Therapy

Researchers Target Tyrosine Kinase in Leukemia

Published in Gene Therapy Weekly, February 27th, 1995

A cancer "smart bomb" that attacks and kills leukemia cells while not harming normal, healthy cells may be tested on humans this summer (1995), a researcher says.

Dr. F.M. Uckun of the University of Minnesota in Minneapolis reported in the journal Science that experiments with laboratory mice prove that an antibody linked to a cancer-killing chemical can effectively wipe out leukemia cells without damaging normal tissue.

He called the technique a smart bomb that might be used against breast, ovary and brain cancers. Though the experiment involved only mice, Uckun said the therapy may be available for clinical testing on humans in summer 1995.

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