Published in Gene Therapy Weekly, February 27th, 1995
Dana R. Leach and Gerald N. Callahan note that most tumor cells express MHC class I, but not class II molecules, and therefore do not stimulate a cellular immune response in the host. For this reason, they investigated the effects of MHC class II gene transfection on the tumorigenic and immunogenic properties of tumor cells ("Fibrosarcoma Cells Expressing Allogeneic MHC Class II Antigens Induce Protective Antitumor Immunity," Journal of Immunology, January 15,...
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.