Published in Gene Therapy Weekly, February 27th, 1995
Research findings from Donald C. Malins et al. also suggest strategies for potentially reversing DNA damage that may be used in prevention and treatment of breast cancer ("The Etiology and Prediction of Breast Cancer," Cancer, January 15, 1995;75(2):503-17).
Previous research has shown that DNA modifications which yield bulky adducts of DNA base structures have primary significance in introducing mutagenic changes in cellular DNA. Cytochrome P-450-catalyzed two-electron oxidation reactions is one...
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