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Cancer/Gene Therapy

Genetically Altered Herpes Virus May Kill Malignant Glioma

Published in Gene Therapy Weekly, March 13th, 1995

A new weapon against a nearly always fatal brain cancer may be developed from a genetically altered herpes virus.

In an experiment using laboratory mice, researchers at the University of Alabama at Birmingham (UAB) and the University of Chicago, Illinois, demonstrated that an altered herpes virus was able to knock out cells of one of the most lethal of human diseases, a brain cancer called malignant glioma.

A report on the research was published in the February 28, 1995, issue of the Proceedings of the National Academy of Sciences.

Dr. C. Yancey Gillespie of the school of medicine at UAB said the gene manipulation turns a very...

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