Cancer/Gene Therapy

M.D. Anderson Patient Receives p53 Injection

Published in Gene Therapy Weekly, March 13th, 1995

A patient with advanced lung cancer has begun receiving treatment with a new form of gene therapy for the disease at the University of Texas M.D. Anderson Cancer Center, hospital officials confirmed last month.

The treatment involves injecting a p53 gene that acts as a brake for cell division into portions of a lung tumor that cannot be removed surgically. The p53 gene attaches to a defective retrovirus which can infect cells but does not reproduce after infection.

Dr. Jack Roth, chairman of Anderson's department of thoracic surgery department, removed as much tumor as he could by surgery and then attempted gene therapy on the remainder.

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Source: Gene Therapy Weekly (1995-03-13)

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