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QT Syndrome

Genes Linked to Sudden Death

Published in Gene Therapy Weekly, March 27th, 1995

People who suffer from one form of life-threatening abnormal heartbeats could benefit from a study that isolated two genes linked to the inherited disorder.

Researchers at the University of Utah, Salt Lake City, conducted a six-year study of long QT syndrome, which causes sudden death in young, otherwise healthy people. The results of the study were published in a March 1995, issue of the medical journal Cell.

In a patient with long QT syndrome, heartbeats become so irregular the flow of blood to the brain and other organs is disrupted and even stopped. Mutated genes cause channels of heart cells to stick open. As a result, the heart rate soars...

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