Hematopoietic Progenitor Cells

Findings Offer Model for HIV Hematopoietic Infection

Published in Gene Therapy Weekly, April 3rd, 1995

Researchers from Italy and the United States stated that their observations provide an experimental model for studies on HIV hematopoietic infection as well as in vitro tests for anti HIV hematopoietic stem cells gene therapy.

C. Chelucci, Istituto Superiore di Sanita, Rome Italy, and colleagues stated that in most patients who are infected with HIV show not only a decrease of CD4⁺ peripheral blood lymphocytes, but also unilineage or multilineage suppression of bone marrow hematopoiesis, (that is, thrombocytopenia, granulocytopenia, anemia, lymphopenia) up to pancytopenia in the late HIV infection stage ("In Vitro Human Immunodeficiency Virus-1 Infection of...

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Source: Gene Therapy Weekly (1995-04-03)

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