Published in Gene Therapy Weekly, April 3rd, 1995
Kostas Pantopoulos and Matthias W. Hentze, European Molecular Biology Laboratory, Heidelberg, Germany, noted that iron-regulatory protein (IRP) is a principal regulator of cellular iron homeostasis ("Nitric Oxide Signaling to Iron-Regulatory Protein: Direct Control of Ferritin mRNA Translation and Transferrin Receptor mRNA Stability in Transfected Fibroblasts," Proceedings of the National Academy of Sciences, February 1995;92:1267-1271).
Pantopoulos and Hentze stated that the expression of several genes that are involved in iron uptake, storage...
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