Nitric Oxide
Role in Regulating Gene Expression Described
Published in Gene Therapy Weekly, April 3rd, 1995
Kostas Pantopoulos and Matthias W. Hentze, European Molecular Biology Laboratory, Heidelberg, Germany, noted that iron-regulatory protein (IRP) is a principal regulator of cellular iron homeostasis ("Nitric Oxide Signaling to Iron-Regulatory Protein: Direct Control of Ferritin mRNA Translation and Transferrin Receptor mRNA Stability in Transfected Fibroblasts," Proceedings of the National Academy of Sciences, February 1995;92:1267-1271).
Pantopoulos and Hentze stated that the expression of several genes that are involved in iron uptake, storage...
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Source: Gene Therapy Weekly (1995-04-03)
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