Published in Gene Therapy Weekly, May 1st, 1995
The peptide, called DP-178, is an analog of a parent peptide created in 1992 by Duke University researcher Carl Wild and colleagues. Wild et al. created the original peptide, DP-107, in order to study the function of the HIV-1 gp41 transmembrane glycoprotein. DP-107 corresponds to amino-acid residues 558 to 595 of gp41.
To their surprise, the peptide had potent anti-HIV activity.
Since their initial discovery, Wild et...
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