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Vectors - Malaria

"Research for Genetic Transformation of Diptera Vectors."

Published in Gene Therapy Weekly, June 12th, 1995

According to an abstract submitted by the authors to the Keystone Symposium entitled Toward the Genetic Manipulation of Insects, held March 17-23, 1995, in Tamarron, Colorado, "We have been working to develop a suitable transfection system towards the goal of obtaining transgenic non-drosophilid insects which will block transmission of human protozoan parasites. The following aspects are being investigated: (1) the development of transfection methods for the introduction of exogenous DNA, (2) analyses of appropriate promoters to control expression of introduced genes, and (3) development of a vector to deliver genes in insects. We have investigated these three topics using either...

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