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Gene Discovery

Blocking Cancer Cells' "Sweet Tooth" May Stop or Kill Malignant Tumors

Published in Gene Therapy Weekly, July 24th, 1995

Researchers at Johns Hopkins, Baltimore, Maryland, have isolated a gene that helps many cancer cells grow and reproduce at rapid rates, and have determined the sequence of DNA building blocks that make up a crucial part of that gene.

The part, known as the regulatory region of the gene, directs production of the first link in a chain of chemical reactions that helps fuel runaway cell growth and reproduction. If doctors can find a way to impede or completely block these reactions, they may be able to slow or even stop the most destructive activities of cancer cells.

"This study helps explain one of the most common biochemical characteristics of many...

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