Published in Gene Therapy Weekly, September 4th, 1995
Roughly 75% of the women diagnosed with ovarian cancer present with surgically incurable advanced disease. Chemotherapy after debulking surgery has increased the 5-year survival rate to 10-20 percent. Drug-resistant cancer cells that exist prior to or develop after treatment are likely to be responsible for the high rate of chemotherapy failure. However, previously discovered drug-resistance mechanisms have failed to be indicative of chemotherapy response in...
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