Transplantation

Rodents May Help Transplants

Published in Gene Therapy Weekly, October 30th, 1995

A substance found in rodent testicles may hold the key to preventing the rejection of transplanted organs, researchers said.

A research team at the University of Colorado Health Sciences Center, Denver, found that a molecule called CD95 ligand in the testicles of mice appears to prevent the rodents' immune systems from killing transplanted cells.

"This could be the magic elixir that we can use to prevent graft rejection," said Donald Bellgrau, associate professor of immunology who reported the results in the October 18, 1995, issue of the journal Nature.

The human body's immune system is the greatest enemy of transplanted cells...

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Source: Gene Therapy Weekly (1995-10-30)

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