HIV Gene Therapy

French Researchers Explore Three Modalities for Treating Infection

Published in Gene Therapy Weekly, November 20th, 1995

French researchers are currently exploring three gene therapy modalities for treating HIV infection.

As HIV predominantly infects cells of the hematopoietic system, stem cells are good potential targets for the introduction of foreign anti-HIV genes. Ex vivo transduction, and then reimplantation of the genetically modified stem cells into HIV infected patients could allow the repopulation of the host with mature CD4⁺ cell populations expressing novel molecules that interfere with viral replication and slow progression into AIDS.

V. Calenda et al., of Transgene and INSERM in France, have developed new gene therapy protocols for the...

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Source: Gene Therapy Weekly (1995-11-20)

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