Antisense Technology
ODNs May Offer Alternative Antimalarial Strategy
Published in Gene Therapy Weekly, February 19th, 1996
In addition, the methodology for identifying essential genes is necessary for the development of other drugs as well, indicated Robert H. Barker, Jr., and colleagues from Hybridon, Inc. and Worcester Foundation for Biomedical Research, Worcester, Massachusetts.
Barker et al. used antisense (AS) oligodeoxynucleotides (ODNs) against various target genes to study growth inhibition of Plasmodium falciparum in in vitro culture ("Inhibition of Plasmodium falciparum Malaria Using Antisense...
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Source: Gene Therapy Weekly (1996-02-19)
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