Published in Gene Therapy Weekly, March 4th, 1996
Viral vectors for gene transduction have their pros and cons. They can efficiently transfer genes into cells, but the structure and stability of the transferred genes are restricted by the virus genome. Nonviral vectors, such as cationic lipid (CL)-DNA complex can transfer genes with little structure restriction, however, they tend to have lower transduction efficiency rates.
An alternative nonviral vector (FL) has been produced by fusing Sendai virus with multilamellar liposomes. FL became a unique delivery system capable of introducing materials encapsulated in the...
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