Breast Cancer (Genetics)

DNA Damage Linked to Risk of Cancer Spread

Published in Gene Therapy Weekly, April 1st, 1996

Malignant cells that break away from breast tumors and spread beyond the breast have characteristic changes in their DNA that may explain why these tumors become so deadly, according to a study by researchers at Pacific Northwest Research Foundation, Seattle, Washington.

The study appeared in the March 19, 1996, issue of the Proceedings of the National Academy of Sciences. In the study, the researchers looked at molecular changes in DNA caused by free radicals, highly reactive molecules that are generated within cells and are known to contribute to aging.

They found that the DNA in tumors that had generated metastases had more than twice the amount...

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Source: Gene Therapy Weekly (1996-04-01)

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