Genetics

Biologists Show That Unpacking DNA is Key To Turning Genes On

Published in Gene Therapy Weekly, April 8th, 1996

By tracking down a long-sought but elusive protein, biologists have for the first time shown that changes in the body's DNA packaging play a key role in turning genes on. This surprises many biologists who have long considered chromatin modification and transcription regulation as separate processes; several scientists expect the finding to cause a redirection in research.

The results and an accompanying review are in the March 22, 1996, issue of the journal Cell.

A University of Rochester team of scientists is the first to clone and sequence a type of enzyme that breaks open the body's way of packing DNA, loosening up the DNA's chromatin package in...

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Source: Gene Therapy Weekly (1996-04-08)

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