Published in Gene Therapy Weekly, April 22nd, 1996
Antisense oligodeoxynucleotides (ODNs) inhibit gene expression by forming RNA-DNA duplexes which prevent messenger RNA (mRNA) translation. Although commonly used to investigate the role of oncogenes in cancer development, and recently entered in clinical trials as therapeutic antineoplastic and anti-HIV agents, their use against solid tumors has only recently been explored.
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.