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Werner's Syndrome

Premature Aging Gene Discovered

Published in Gene Therapy Weekly, April 22nd, 1996

Scientists have taken the first step toward unlocking genetic mysteries of aging, discovering a gene that one day might lead to treatments for - or even slowing of - diseases that hit the elderly.

The gene causes Werner's syndrome, which turns 20-year-olds' hair gray and gives them ailments more common to grandparents. Unraveling this premature aging should help doctors better understand normal aging.

"A kind of Holy Grail of aging research has been to find this gene," said Gerard Schellenberg, whose team at the Seattle Veterans Affairs Medical Center won an international race to identify the gene named WRN. The gene appears to play a vital role in...

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