Conference Coverage (IBC Vaccines)

Artificial Cell Vaccine for Tumor Therapy

Published in Gene Therapy Weekly, May 6th, 1996

Artificial cells created by the attachment of immunogenic molecules to tumor-cell membranes could be used to treat cancers, an Emory University, Atlanta, Georgia, researcher suggests.

Tumor cells avoid stimulating antitumor immune responses because they do not express the so-called costimulatory molecules that must be presented together with antigen for immune recognition.

Current approaches to the development of therapeutic tumor vaccines include engineering tumor cells to express gene major costimulatory molecules such as B7.

Researcher Periasamy Selvaraj suggests an alternative: the creation of an antitumor vaccine by...

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Source: Gene Therapy Weekly (1996-05-06)

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