Renal Cancer

Mutated Gene Identified

Published in Gene Therapy Weekly, May 20th, 1996

Scientists have isolated a gene on human chromosome 3 that is mutated in patients with renal cancers, according to a report from the Barbara Ann Karmanos Cancer Institute.

The Institute is affiliated with The Detroit Medical Center and Wayne State University.

The gene, called ARP for arginine-rich protein, was identified in chromosomal band 3p21, a region that is frequently deleted in a variety of cancers, including lung, breast, prostate and kidney cancers. All the mutations occurred within one small region of the ARP gene.

Viji Shridhar, Ph.D., and David Smith, Ph.D., of the Barbara Ann Karmanos Cancer Institute noted that the...

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Source: Gene Therapy Weekly (1996-05-20)

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