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Discovery of Damaged Gene Boosts Cancer Research

Published in Gene Therapy Weekly, July 22nd, 1996

The discovery of a damaged gene in well over half the most common forms of cancer gives the best hope of a cancer cure, researchers said.

"I'm very optimistic," said David Lane, Dundee University, Scotland, who discovered the tumor-suppressing gene p53 in 1978. "There has been more progress toward finding the causes of cancer - and therefore possible treatments - in the last 15 years than ever before."

Lane said damaged p53 genes were found in more than 50 percent of cancer patients. Damaged p53 genes were found in all the main cancers - those affecting brain, lungs, breast, colon or prostate.

The gene detects and kills damaged...

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