"Effect of Estrogen on the Regulation of Cytochrome P450IAI Gene Expression in MCF-7 Human Breast Cancer Cells."

According to an abstract submitted by the authors to the 10th International Congress of Endocrinology, sponsored by the International Society of Endocrinology and the Endocrinology Society, held June 12-15, 1996, in San Francisco, California, "Since arylhydrocarbon hydroxylase activity was abundant in MCF-7 human breast cancer cells, complementary DNA of cytochrome P450IAI was cloned from these cells. However, it is not known why MCF-7 cells maintain arylhydrocarbon hydroxylase activity at relatively high level when they are compared to other cells. In order to understand the mechanism of the regulation of arylhydrocarbon hydroxylase activity, we undertook a study to examine the effect...

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