Cancer Gene Therapy
"Down-Regulation of Prostate Specific Antigen in Human CWR22 Xenograft: An Ex Vivo Tumor Model for Prostate Cancer Gene Therapy."
Published in Gene Therapy Weekly, September 16th, 1996
According to an abstract submitted by the authors to a joint meeting of the American Society for Biochemistry and Molecular Biology, the American Society for Investigative Pathology, and the American Association of Immunologists, held June 2-6, 1996, in New Orleans, Louisiana, "We evaluated in this study the application of an ex vivo gene transfer approach for human prostate cancer gene therapy. We constructed and established a transgenic human tumor model, consisting of three major components: 1) human primary prostate cancer cells, a recently reported androgen-dependent, transplantable xenograft (CWR22), derived from a primary human prostate carcinoma, 2) a collagen gel, ex vivo tissue...
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Source: Gene Therapy Weekly (1996-09-16)
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