"Treatment of 9L Gliosarcoma with IL-4 Producing 9L Vaccine."

According to an abstract submitted by the authors to a joint meeting of the American Society for Biochemistry and Molecular Biology, the American Society for Investigative Pathology, and the American Association of Immunologists, held June 2-6, 1996, in New Orleans, Louisiana, "We have demonstrated previously that interleukin-4 (IL-4) promotes T-cell dependent anti-tumor activity against the 9L gliosarcoma in Fischer rats. 9L gliosarcoma cells transfected with an mIL-4 cDNA and secreting 20 ng IL-4/48h/10⁶ cells are 97% growth inhibited after implantation in the Fischer rat central nervous system and are eliminated, following a brief period of growth, within 30 days after...

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