Published in Gene Therapy Weekly, September 23rd, 1996
In vivo gene therapy is dependent on safe and efficient vectors for mediating DNA transfer. An alternative to the inherent problems associated with viral vectors is the use of cationic liposomal vectors. Unfortunately, these vectors, although considered safe, are relatively inefficient in comparison to their viral counterparts.
In response to the need to develop gene delivery systems that are safe and can be selectively targeted to specific cells, Grace Y. Kao et al., from the University of Alberta, Canada, hypothesized that the...
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