"The Molecular Basis for Virulence."

According to an abstract submitted by the author to the 36th Interscience Conference on Antimicrobial Agents and Chemotherapy, held September 15-18, 1996, in New Orleans, Louisiana, "The application of new technologies for genetic analysis is now providing a rigorous and powerful paradigm for a definition of the molecular basis of group A streptococcal virulence. Targeted gene deletion and allelic replacement have been used to both to confirm the important role of the M protein in virulence and to identify novel adhesions like the fibronectin-binding protein, protein F. Transposon mutagenesis strategies have been used to identify transcriptional regulators of M protein (mga) and protein...

Want to see the full article?

• Purchase this article for only $3.00