Published in Gene Therapy Weekly, November 4th, 1996
Recent research has demonstrated the antitumoral effect of retrovirally-mediated suicide gene therapy using herpes simplex virus 1/thymidine kinase (HSV/tk) followed by ganciclovir administration as well as the immunotherapeutic effects of retroviral-mediated transduction of murine interleukin-2 (mIL-2). In addition, both techniques have been tested using adenoviral vectors with a certain degree of success in some animal models.
Instead of testing the vectors...
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