Cancer Vaccines
"Highly Efficient Ex Vivo-Gene Transfer into Primary Human Tumor Cells using Improved Recombinant Adeno-Associated Virus (rAAV) Vectors."
Published in Gene Therapy Weekly, December 23rd, 1996
According to an abstract submitted by the authors to the 38th Annual Meeting of the American Society of Hematology, held December 6-10, 1996, in Orlando, Florida, "Background: Adeno-associated virus (MV) is a single-stranded DNA parvovirus which has advantageous features as a gene transfer vector like its ability to transduce terminally differentiated non-dividing cells, its lack of pathogenicity, its low immunogenicity, and a relatively stable transgene expression. Using an improved packaging method (Hum Gene Ther 6:1531, 1995) we evaluated the potential of rAAV vectors for tumor vaccination. Methods: Different rAAV vectors containing the reporter genes...
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Source: Gene Therapy Weekly (1996-12-23)
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