Gene Therapy Weekly

Susan Hasty, Publisher

Table of Contents . . . January 27th, 1997

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Gene Therapy Weekly | Other Publications

Corrective Gene Therapy (CGD) - Gene Transfer Corrects Defect in Host Defense against Infection

Antisense Technology - Anticancer Drug Demonstrates Antitumor Activity In Vivo

Antisense Technology - Compound Aimed at Reducing Serum Cholesterol Levels

Breast Cancer - 'Switched On' Gene in Cancer Cells Remains 'Turned Off' in Normal Tissue

Breast Cancer - Random Homozygous Knockout Method Discovers Cancer Gene

Cancer Gene Therapy - Transfection of Chronic Lymphocytic Leukemia B Cells Possible

Industry News (Joint Venture) - Collaboration Established for Combinatorial Drug Discovery

Industry News (Joint Venture) - Collaboration Extension Agreement for Viral Gene Regulation Announced

Industry News (Joint Venture) - DNA Sequenced by Time-of-Flight Mass Spectrometry

Industry News (Joint Venture) - Gene Discovery Collaboration Announced for Prostate Cancer

Industry News (Joint Venture) - Merger Establishes Gene Therapy Company

Neuroscience - Adenovirus Vector Transfects Embryonic Glial and Neuronal Cells

Suicide Gene Therapy - Bystander Effect Inhibited by the Drug Verapamil

Vector Development - Modified Herpes Vector Efficiently Transfects Hematopoietic Cells

Animal Models (Gene Therapy) - "Transplantation of Autologous Cultured Hepatocytes in Primate: A Model for Gene Therapy of Congenital Hypercholesterolemia."

Gene Transfer Efficiencies - "In Vivo Gene Transfer to Hepatocellular Carcinoma (HCC) in Experimental Animal Models by Adenoviral Vector."

Genetic Manipulation - "Adenovirus-Mediated Gene Transfer of Thrombomodulin to Human Endothelial Cells: Effects on Thromboresistance and In Vitro Clotting."

HIV Vaccines - "HIV Vaccines - Towards Phase III."

In Utero Gene Therapy - "In Utero Transplacental Adenoviral Gene Transfer to Murine Fetal Heart."

Pathogenesis (Adenovirus Vector) - "In Vivo Gene Transfer Using Replication Deficient Adenovirus Vector Alters Vasomotricity in Rabbit Arteries."

Somatic Gene Therapy - "Transduction of Hepatocellular Carcinoma (HCC) Cells Using Recombinant Adeno-Associated Virus (AAV) Vector."

Transfusion Medicine - "Activated Protein C-Mediated Inactivation of Recombinant Human Factor Va."

Transplantation Medicine - "Human VEGF Gene Transfer into Vascular Prosthesis."

Antisense Technology - "Relative Levels of Inhibition of p24 Gene Expression by Different 20-mer Antisense Oligonucleotide Sequences Targeting Nucleotides +1129 to +1268 of the HIV-1 Gag Genome: An Analysis of Mechanism."

Cancer Gene Therapy - "Adenoviral Infection of Thyroid Cells: A Rationale for Gene Therapy for Metastatic Thyroid Carcinoma."

Cancer Gene Therapy - "Expression of p53 in Saos-2 Osteosarcoma Cells Induces Apoptosis Which Can Be Inhibited by Bcl-2 or the Adenovirus E1B-55 kDa Protein."

Cardiology - "Long-Term Gene Transfer in Porcine Myocardium after Coronary Infusion of an Adeno-Associated Virus Vector."

Hemophilia - "Implantation of Autologous Skin Fibroblast Genetically Modified to Secrete Clotting Factor IX Partially Corrects the Hemorrhagic Tendencies in Two Hemophilia B Patients."

Hypertension - "In vivo Gene Transfer and Gene Modulation in Hypertension Research."

Melanoma - "Active Specific Immunotherapy of Pulmonary Metastasis with Vaccinia Melanoma Oncolysate Prepared from Granulocyte/Macrophage Colony-Stimulating-Factor-Gene-Encoded Vaccinia Virus."

Melanoma - "Transcriptional Targeting of Recombinant Adenoviruses to Human and Murine Melanoma Cells."

Obesity - "Correction of Obesity and Diabetes in Genetically Obese Mice by Leptin Gene Therapy."

Obesity - "Disappearance of Body Fat in Normal Rats Induced by Adenovirus-Mediated Leptin Gene Therapy."

Somatic Gene Therapy - "Human Somatic Cell Gene Therapy."

Vectors - "Adenovirus Infection Stimulates the Raf/MAPK Signaling Pathway and Induces Interleukin-8 Expression."

Vectors - "Characterization of a Replication-Incompetent Adenovirus Type 5 Mutant Deleted for the Preterminal Protein Gene."

Vectors - "Induction of Central Tolerance by Intrathymic Inoculation of Adenoviral Antigens into the Host Thymus Permits Long-Term Gene Therapy in Gunn Rats."

Vectors - "Toward Highly Efficient Cell-Type-Specific Gene Transfer with Retroviral Vectors Displaying Single-Chain Antibodies."

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