Cancer Gene Therapy

Suicide Gene Therapy Effective in Murine Model of Ovarian Cancer

Published in Gene Therapy Weekly, February 3rd, 1997

Adenovirus-mediated transfection of the herpes simplex virus thymidine kinase (HSVtk) gene (Ad.RSVtk) followed by ganciclovir (GCV) administration modulates ovarian cancer cell growth in vitro and in vivo in a murine model.

The overall five-year survival rate for ovarian cancer is a dismal 37 percent. Poor survival rates are related directly to the late stage of detection of this disease. There are no reliable early diagnostic procedures, so the burden of improving survival rates currently falls on therapeutic procedures.

Kian Behbakht and colleagues from the University of Pennsylvania tested the feasibility of adenovirus-mediated...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of Gene Therapy Weekly

Source: Gene Therapy Weekly (1997-02-03)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry